https://doi.org/10.4081/ltj.2025.406

Laser excision of benign skin lesions: a comparative analysis of two CO2 laser systems

Vol. 32 No. 1 (2025)
Submitted: 7 September 2024
Accepted: 2 January 2025
Published: 22 January 2025
CO2 laser, benign skin lesion, excision
Abstract Views: 99
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Authors

Arminda Avdulaj
avdulajarminda@gmail.com
San Luca Medical Clinic, Tirana, Albania.

Lasers are common dermatological tools used for both clinical and aesthetic indications. The CO2 laser is the gold standard system used for ablative removal of benign lesions. Due to its high absorption in water and low ablation threshold, it can be used to remove, cut, and coagulate skin tissue. This retrospective analysis compared the 3-month safety and performance of the Alma Hybrid/Hylight 50 and Pixel CO2 Focus laser systems used to remove benign skin lesions in adult patients. Treatment tolerability was rated immediately after the procedure, while clearance and patient satisfaction with treatment outcomes were assessed at the 6-month follow-up visit. Overall, 37 lesions were excised with the Hybrid/Hylight 50 laser, and 41 lesions were excised with the Pixel CO2/Focus laser. In both cohorts, 70% of the lesions removed were intradermal nevi or skin tags, all lesions were nonvascular, and most were located on the face (Hybrid/Hylight: 75.7%; Pixel CO2/Focus: 61.0%). Median lesion size was 7.65 mm and 7.09 mm in the Hybrid/Hylight and Pixel/Focus cohorts, respectively. Complete removal of all lesions was achieved after a single treatment session, regardless of the laser system used. Patients reported very low pain levels and were highly satisfied with the treatment outcomes. Hypopigmentation was reported for two patients in the Hybrid/Hylight cohort and 1 patient in the Pixel cohort; 1 patient in each cohort developed post-inflammatory hyperpigmentation. All adverse events resolved within 5-10 months. Our findings indicate that CO2 lasers can safely and effectively remove benign skin lesions of varying sizes and locations on the body.

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Europe PMC
1. Campolmi P, Bonan P, Cannarozzo G, et al. Highlights of thirty-year experience of CO2 laser use at the Florence (Italy) department of dermatology. ScientificWorldJournal 2012;2012:546528. DOI: https://doi.org/10.1100/2012/546528
2. Conforti C, Vezzoni R, Giuffrida R, et al. An overview on the role of CO(2) laser in general dermatology. Dermatol Ther 2021;34:e14692. DOI: https://doi.org/10.1111/dth.14692
3. Klein A, Baumler W, Landthaler M, Babilas P. Laser thermal therapy of benign skin tumours: review and update. Int J Hyperthermia 2011;27:762-70. DOI: https://doi.org/10.3109/02656736.2011.599049
4. Ohshiro T. Auto-simultaneous laser treatment: a new effect-based classification. Laser Therapy 2005;14:11-7. DOI: https://doi.org/10.5978/islsm.14.11
5. McKenzie AL. How far does thermal damage extend beneath the surface of CO2 laser incisions? Phys Med Biol 1983;28:905-12. DOI: https://doi.org/10.1088/0031-9155/28/8/003
6. Kose O. Efficacy of the carbon dioxide fractional laser in the treatment of compound and dermal facial nevi using with dermatoscopic follow-up. J Dermatolog Treat 2019;30:498-502. DOI: https://doi.org/10.1080/09546634.2018.1529384
7. Eggen CAM, Lommerts JE, van Zuuren EJ, et al. Laser treatment of congenital melanocytic naevi: a systematic review. Br J Dermatol 2018;178:369-83. DOI: https://doi.org/10.1111/bjd.16094
8. Omi T, Numano K. The Role of the CO2 Laser and Fractional CO2 Laser in Dermatology. Laser Ther 2014;23:49-60. DOI: https://doi.org/10.5978/islsm.14-RE-01
9. Zaresharifi S, Robati RM, Dadkhahfar S, et al. Efficacy and safety of cryotherapy, electrodesiccation, CO2 laser, and Er:YAG laser in the treatment of seborrheic keratosis. Dermatol Ther 2021;34:e15083. DOI: https://doi.org/10.1111/dth.15083
10. Cheyasak N, Manuskiatti W, Maneeprasopchoke P, Wanitphakdeedecha R. Topical corticosteroids minimise the risk of postinflammatory hyper-pigmentation after ablative fractional CO2 laser resurfacing in Asians. Acta dermato-venereologica 2015;95:201-5. DOI: https://doi.org/10.2340/00015555-1899
11. Bin Dakhil A, Shadid A, Altalhab S. Post-inflammatory hyperpigmentation after carbon dioxide laser: review of prevention and risk factors. Dermatol Rep 2023;15:9703. DOI: https://doi.org/10.4081/dr.2023.9703
12. Alster TS, Li MK. Dermatologic Laser Side Effects and Complications: Prevention and Management. Am J Clin Dermatol 2020;21:711-23. DOI: https://doi.org/10.1007/s40257-020-00530-2
13. Raulin C, Kimmig W. Laser Therapy in Dermatology and Aesthetic Medicine: Side Effects, Complications, and Treatment Errors. In: Kautz G, ed. Energy for the Skin: Effects and Side-Effects of Lasers, Flash Lamps and Other Sources of Energy. Cham: Springer International Publishing; 2022:13-25. DOI: https://doi.org/10.1007/978-3-030-90680-1_2

How to Cite

Avdulaj, A. (2025). Laser excision of benign skin lesions: a comparative analysis of two CO<sub>2</sub> laser systems. Laser Therapy, 32(1). https://doi.org/10.4081/ltj.2025.406
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