https://doi.org/10.4081/ltj.2023.324

Phototherapy (photobiomodulation) for peripheral nerve and muscle injury

Vol. 30 No. 1 (2023)
Published: 4 September 2023
Phototherapy, photobiomodulation, peripheral nerve and muscle injury
Abstract Views: 2703
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Authors

Shimon Rochkind
rochkind@zahav.net.il
Specialist in Neurosurgery & Microsurgery, Head, Microsurgical Center for Peripheral Nerve Reconstruction, Assuta Medical Center, Tel Aviv, Israel.

Severe peripheral nerve and muscle injuries are a highly prevalent condition for both civilians and military personnel caused by traffic accidents, work injuries, acts of violence, as well as combat events.

Peripheral nerve injury is a substantial problem that annually affects more than several millions of people all over the world. For most patients who suffer from severe peripheral nerve injuries spontaneous recovery may eventually occur, but it is slow and frequently incomplete. Effective posttraumatic nerve repair and decrease or prevention of corresponding muscle atrophy remain a great challenge to restorative medicine. A certain clinical interest began to appear in the potential therapeutic value of laser phototherapy (new name – laser photobiomodulation) for regeneration enhancement of injured peripheral nerve as well as for restoration or prevention of denervated muscle atrophy. Although a pioneering report regarding the effects of laser phototherapy on the regeneration of traumatically injured peripheral nerves was published in the late 1970s,1 it is only since the end of past century - early 2000s that scientific interest in this therapeutic approach for neural rehabilitation has appeared, leading to publication of several studies that have shown positive effects of phototherapy on peripheral nerve regeneration.2 [...]

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Rochkind S. Stimulation effect of laser energy on the regeneration of traumatically injured peripheral nerves. Morphogen Regen 1978;83:25-27.
Gigo-Benato D, Geuna S, Rochkind S. Phototherapy for enhancing peripheral nerve repair: a review of the literature. Muscle Nerve 2005;31:694-701. DOI: https://doi.org/10.1002/mus.20305
Rochkind S. Phototherapy in peripheral nerve regeneration: From basic science to clinical study. Neurosurg Focus 2009;26:E8. DOI: https://doi.org/10.3171/FOC.2009.26.2.E8
Shamir MH, Rochkind S, Sandbank J, Alon M. Double-blind randomized study evaluating regeneration of the rat transected sciatic nerve after suturing and postoperative low power laser treatment. J Reconstruct Microsurg 2001;17:133-138. DOI: https://doi.org/10.1055/s-2001-12702
Rochkind S, Leider-Trejo L, Nissan M, et al. Efficacy of 780-nm laser phototherapy on peripheral nerve regeneration after neurotube reconstruction procedure (double-blind randomized study). Photomed Laser Surg 2007;25:137-143. DOI: https://doi.org/10.1089/pho.2007.2076
Gigo-Benato D, Geuna S, de Castro Rodrigues A, et al. Low-power laser biostimulation enhances nerve repair after end-to-side neurorrhaphy: A double-blind randomized study in the rat median nerve model. Laser Med Sci 2004;19:57-65. DOI: https://doi.org/10.1007/s10103-004-0300-3
Rochkind S, Drory V, Alon M, et al. Laser phototherapy (780 nm), a new modality in treatment of log-term incomplete peripheral nerve injury: A randomized double-blind placebo-controlled study. Photomed Laser Surg 2007;25:436-442. DOI: https://doi.org/10.1089/pho.2007.2093
Rochkind S, Shainberg A. Protective effect of laser phototherapy on acetylcholine receptors and creatine kinase activity in denervated muscle. Photomed Laser Surg 2013;31:499-504. DOI: https://doi.org/10.1089/pho.2013.3537
Rochkind S, Geuna S, Shainberg A. Phototherapy and nerve injury: focus on muscle response. Inter Rew Neurobiol 2013;109:99-109. DOI: https://doi.org/10.1016/B978-0-12-420045-6.00004-3
Mandelbaum-Livnat M, Almog M, Nissan M, et al. Photobiomodulation triple treatment in peripheral nerve injury: nerve and muscle response. Photomed Laser Surg 2016;34:638-645. DOI: https://doi.org/10.1089/pho.2016.4095
Andreo L, Ribeiro B, Alves A, et al. Effects of photobiomodulation with low-level laser therapy on muscle repair following a peripheral nerve injury in Wistar rats. Photochem Photobiol 2020;96:1124-1132. DOI: https://doi.org/10.1111/php.13255
Almog M, Nissan M, Koifman I, et al. On-site laser photobiomodulation treatment of crushed muscle due to prolonged pressure in rats. Laser Surg Med 2021;53:1258-1265. DOI: https://doi.org/10.1002/lsm.23417
Falcai MJ, Monte-Raso VV, Okubo R, et al. Biomechanical and histological analysis of the gastrocnemius in rats subjected to muscle injury and treatment with low-level laser therapy. Rev Bras Ortop 2010;45:444-448. DOI: https://doi.org/10.1016/S2255-4971(15)30395-5
Rizzi CF, Mauriz JL, Freitas Corrêa DS, et al. Effects of low-level laser therapy (LLLT) on the nuclear factor (NF)-kappaB signaling pathway in traumatized muscle Lasers Surg Med 2006;38:704-713. DOI: https://doi.org/10.1002/lsm.20371
Silveira PC, da Silva LA, Pinho CA, et al. Effects of low-level laser therapy (GaAs) in an animal model of muscular damage induced by trauma. Lasers Med Sci 2013;28:431-436. DOI: https://doi.org/10.1007/s10103-012-1075-6
Iyomasa DM, Garavelo I, Iyomasa MM, et al. Ultrastructural analysis of the low-level laser therapy effects on the lesioned anterior tibial muscle in the gerbil. Micron 2009;40:413-418. DOI: https://doi.org/10.1016/j.micron.2009.02.002

How to Cite

Rochkind, S. (2023). Phototherapy (photobiomodulation) for peripheral nerve and muscle injury. Laser Therapy, 30(1). https://doi.org/10.4081/ltj.2023.324
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