https://doi.org/10.4081/ltj.2023.321 Real-life efficacy interstitial laser therapy treating laxity of the periorbital region PDF Vol. 30 No. 1 (2023) Submitted: 29 June 2023 Accepted: 24 July 2023 Published: 31 July 2023 Interstitial laser therapy, skin laxity, periorbital region Abstract Views: 2441 PDF: 106 Publisher's note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher. Authors Luca Zattoni zattluca@me.com https://orcid.org/0009-0002-0244-0926 Cosmetic surgeon, Cantù (CO) and Milan, Italy. Alessia Forlin Biomedical engineer, Cantù (CO) and Milan, Italy. Abstract Skin laxity in the periorbital region is a common problem that is usually treated surgically. This is not only invasive, but it also increases the risks for the patient and can result in scarring. Innovative therapies involving the use of the most recent generation of interstitial lasers allow for safe, minimally invasive, and effective intervention in patients suffering from blepharochalasis and periorbital bags. A 100% Made in Italy intra-tissue laser lifting technology, in particular, delivers energy to the subcutaneous tissue via laser fibers as small as 200/300 microns, ensuring a targeted release of energy and allowing the formation of new collagen while decreasing skin laxity. The purpose of this study is to assess the effect of an interstitial laser using optical microfibers on 5 patients aged 30 to 60 years. Following anesthesia (Lidocaine and Adrenaline), the treatment was performed using an endotissue laser with a wavelength of 1470 nm. The cumulative energy delivered by the laser by using 300-micron disposable fibers is equal to 200 Joules for each lid, with an infrared thermometer confirming an increase in skin temperature not exceeding 40°C. Over the next six months, patients experienced optimal results with no visible skin signs. In conclusion, we can state that intra-tissue laser lifting can be an effective strategy for the treatment of periorbital laxity, resulting in a decrease in dermal laxity and greater skin homogeneity while ensuring high precision, the absence of superficial incisions, rapid recovery, and optimal results. Metrics Dimensions Altmetric PlumX Metrics Downloads Download data is not yet available. Citations References Nilforoushzadeh MA, Heidari-Kharaji M, Fakhim T, et al. Efficacy of Endolift laser for arm and under abdomen fat reduction. J Cosmet Dermatol 2023;22:2018-22. DOI: https://doi.org/10.1111/jocd.15684 Nilforoushzadeh MA, Heidari-Kharaji M, Behrangi E, et al. Effect of Endolift laser on upper eyelid and eyebrow ptosis treatment. J Cosmet Dermatol 2022;21:3380-5. DOI: https://doi.org/10.1111/jocd.14798 Bartoletti E, Alessandrini A, Di Leo A. Soft lifting con fibra ottica laser: un nuovo approccio nel contouring del terzo inferiore del volto. Fondazione Fatebenefratelli Roma Scuola Internazionale di Medicina Estetica. Thesis, 2020. Pepe NR, Argenzio V, Cerno G, et al. Thermo-induced hystopathology of animal superficial tissues as a consequence of interstitial application of laser (924+975 nm, 980 nm, 1470 nm) and radiofrequency (1 and 4 Mhz): A study on bench. J Plastic Dermatol 2014;10:115-124. Available from: https://www.researchgate.net/publication/289753924_Thermo-induced_hystopathology_of_animal_superficial_tissues_as_a_consequence_of_interstitial_application_of_laser_924975_nm_980_nm_1470_nm_and_radiofrequency_1_and_4_mhz_A_study_on_bench Sadoughifar R, Kaliterna D, Abdelmaksoud A, Türsen B. Topical treatment of acne vulgaris: Endolift® direct optical energy combined with LIGHTSCAN™ fractional laser. J Appl Cosmetol 2023;41:49-52. Sadoughifar R, Kaliterna D, Llergo Valdez RJ, et al. Nonsurgical eyelid ptosis: topical treatment with Endolift® direct optical energy. J Appl Cosmetol 2023;41:33-36. DOI: https://doi.org/10.56609/jac.v41i1.70 Cassuto D, Pignatti M, Pacchioni L, et al. Management of complications caused by permanent fillers in the face: a treatment algorithm. Plast Reconstr Surg 2016;138:215e-27e. DOI: https://doi.org/10.1097/PRS.0000000000002350 Nilforoushzadeh MA, Fakhim T, Heidari-Kharaji M, et al. Endolift laser an effective treatment modality for forehead wrinkles and frown line. J Cosmet Dermatol 2022;21:2463-8. DOI: https://doi.org/10.1111/jocd.14884 McBean JC, Katz BE. Laser lipolysis: an update. J Clin Aesthet Dermatol 2011;4:25-34. Dell’Avanzato R. Endolift®: the “lunch-time” laser lifting for the lower eyelids. Laser Ther J 2022;29:307. DOI: https://doi.org/10.4081/ltj.2022.307 Citation / Copyright How to Cite Zattoni, L., & Forlin, A. (2023). Real-life efficacy interstitial laser therapy treating laxity of the periorbital region. Laser Therapy, 30(1). https://doi.org/10.4081/ltj.2023.321 More Citation Formats ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver Download Citation Endnote/Zotero/Mendeley (RIS) BibTeX Copyright (c) 2023 the Author(s) This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published. Similar Articles Antonio Leccisotti, Stefania V. 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