https://doi.org/10.4081/ltj.2022.297

Therapeutic processes for eradicating cancerous or benign tumours by laser beams using the excitonic approach of peptide groups

Vol. 29 No. 1 (2022)
Published: 30 June 2022
Cancer, radiotherapy, heat transport in biological tissues, protein denaturation, peptide groups
Abstract Views: 1227
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Authors

Jose Ivan Charles Zambe
Physics Department, Laboratoire de Sciences des Matériaux -Faculty of Science, University of Yaounde I, P.O. Box 812 Yaounde, Cameroon.
Elie Simo
esimotc@yahoo.com
Physics Department, Laboratory of Energy and Environment – Faculty of Science, University of Yaounde I, P.O. Box 812 Yaounde, Cameroon.
Dylan Kouam Kuicheu
Physics Department, Laboratoire de Sciences des Matériaux -Faculty of Science, University of Yaounde I, P.O. Box 812 Yaounde, Cameroon.
Péguy Rompavel Fono Fotso
Physics Department, Laboratoire de Sciences des Matériaux -Faculty of Science, University of Yaounde I, P.O. Box 812 Yaounde, Cameroon.
Hakim Souleman Abdel
Physics Department, Laboratory of Energy and Environment – Faculty of Science, University of Yaounde I, P.O. Box 812 Yaounde, Cameroon.

The aim of the present study was to develop a protocol for the treatment of cancerous or benign tumours making use of laser rays, also demonstrating that the destruction process remains exclusively confined in the defective organ. Thermal effects of lasers on biological tissue have been elucidated using vibrational excitations approach of peptide groups (PGs). It was proposed a Hamiltonian which integrate excitations induced by laser pulses and it was shown that the system is governed by a nonlinear equation with strong nonlinearity. It was also exactly described what happens in polypeptide chain once the unwanted organ is irradiated by the Neodymium-doped yttrium aluminium garnet, chosen as incident laser. It was shown that, the advent of incident laser beams contributes to a sudden reinforcement of the vibrational excitations of PGs frequencies and amplitudes. It was also demonstrated that the heating process leads to transverse and longitudinal deformation of the polypeptide chain and these sudden changes lead to the denaturation and subsequently to the destruction of the bulky organ. The drawn curves make it possible to estimate the spatial expansion of the denaturation, in order to effectively control the spread of the heat. Laser irradiation leads to a drastic increase in the vibration amplitudes of the PGs and subsequently results in the destruction of the undesirable tissue. An appropriate choice of the laser can make it possible to circumscribe the destruction only in the defective zone and to protect healthy cells.

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How to Cite

Zambe, J. I. C., Simo, E., Kuicheu, D. K., Fono Fotso, P. R., & Abdel, H. S. (2022). Therapeutic processes for eradicating cancerous or benign tumours by laser beams using the excitonic approach of peptide groups. Laser Therapy, 29(1), 107–114. https://doi.org/10.4081/ltj.2022.297
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